Lasers and intense pulsed light (IPL) association with cancerous lesions.
Lasers Med Sci. 2017 Nov;32(8):1927-1933. doi: 10.1007/s10103-017-2310-y. Epub 2017 Sep 7.
The development and use of light and lasers for medical and cosmetic procedures has increased exponentially over the past decade. This review article focuses on the incidence of reported cases of skin cancer post laser or IPL treatment. The existing evidence base of over 25 years of laser and IPL use to date has not raised any concerns regarding its long-term safety with only a few anecdotal cases of melanoma post treatment over two decades of use; therefore, there is no evidence to suggest that there is a credible cancer risk. Although laser and IPL technology has not been known to cause skin cancer, this does not mean that laser and IPL therapies are without long-term risks. Light therapies and lasers to treat existing lesions and CO2 laser resurfacing can be a preventative measure against BCC and SCC tumour formation by removing photo-damaged keratinocytes and encouraged re-epithelisation from stem cells located deeper in the epidermis. A review of the relevant literature has been performed to address the issue of long-term IPL safety, focussing on DNA damage, oxidative stress induction and the impact of adverse events.
Actinic keratosis (AK); Basal cell carcinoma (BCC); Intense pulsed light (IPL); Malignant melanoma (MM).; Squamous cell carcinoma (SCC); Ultraviolet (UV)
Photomed Laser Surg. 2016 Oct;34(10):435-447. Epub 2016 Sep 30.
Intense Pulsed Light: From the Past to the Future.
For 20 years, intense pulsed light (IPL) technology has been used to treat various medical problems. IPL has since developed rapidly, becoming popular among patients worldwide. Recently, IPL has been used mainly for cosmetic purposes. Researchers are constantly seeking new applications of IPL to meet the increasing needs of patients.
This review summarizes the development of IPL devices, discusses the current literature on the clinical application of IPL to increase our understanding of IPL, and provides guidance for broadening its clinical applications.
MATERIALS AND METHODS:
We performed a systematic search of electronic databases, including MEDLINE and PubMed and the authors experience on IPL to divide IPL development into three stages: germination, growth, and relative maturity.
Studies established the classical indications of IPL, including vascular lesions, pigmented lesions, hair growth, and photo rejuvenation. However, trials showed IPL has limited effects for complicated skin problems. Many studies explored rational combination therapies by IPL and laser or other cosmetic technologies.
Based on previous research and the new generation of IPL devices, in the future, we predict wider and more effective clinical applications of IPL through the further improvement of IPL devices and their combined treatment.
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